In this episode, Marc and Mo are joined by special guest Javad Parvizi (James Edwards Professor of Orthopaedic Surgery at the Sidney Kimmel School of Medicine at the Rothman Institute at Thomas Jefferson University in Philadelphia) in a thought-provoking discussion on the goals and impact of international efforts to achieve consensus and standardization in orthopaedic care, with a specific focus on guidelines related to periprosthetic joint infection and venous thromboembolism. OrthoJOE Mailbag: feedback, comments, and suggestions from our audience can be sent to orthojoe@jbjs.org Links: • Second International Consensus Meeting (ICM) on Musculoskeletal Infection. https://icmphilly.com/ • Parvizi J, Gehrke T, Chen AF. Proceedings of the International Consensus on Periprosthetic Joint Infection. Bone Joint J. 2013 Nov;95-B(11):1450-2. https://online.boneandjoint.org.uk/doi/full/10.1302/0301-620X.95B11.33135?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org