In this episode, Mo and Marc are joined by special guest Professor Rudolf Poolman (Leiden University, OLVG) in a discussion about evidence-based management, leadership, curiosity, Stoicism, and the importance of questioning everything. Links: • Ioannidis JP. Why most published research findings are false. PLoS Med. 2005 Aug;2(8):e124. doi: 10.1371/journal.pmed.0020124. Epub 2005 Aug 30. Erratum in: PLoS Med. 2022 Aug 25;19(8):e1004085. doi: 10.1371/journal.pmed.1004085. PMID: 16060722; PMCID: PMC1182327. https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124 • Seneca, Ad Lucilium Epistulae Morales (Moral Letters to Lucilius) https://en.wikisource.org/wiki/Moral_letters_to_Lucilius Subspecialties: • Orthopaedic Essentials Keywords: Orthopaedics, orthopedics, JBJS, OrthoEvidence, evidence-based medicine, research, leadership, evidence-based management, Stoicism, never-perfect philosophy, KPIs, step-wedge trials, platform trials, hypothesis testing, data science, academia, nursing, administrators, curiosity, journaling, personal vision statement, ChatGPT, CBT, cognitive-behavioral therapy, infection, clinical trials, observational studies, RCTs, impact, productivity vs. impact, changing practice, funding, guidelines, co-creation process, insurance, implementation, hybrid trials, Seneca, Moral Letters to Lucilius