In this episode, Mo and Marc take a look back at several highly viewed studies that were published in The Journal in 2025 and share their predictions of what will shape the field of orthopaedics in 2026. Subspecialties: • Orthopaedic Essentials • Ankle • Knee Link: • Khojaly R, Rowan FE, Shah V, Nagle M, Shahab M, Ahmad AS, Dahly D, Taylor C, Niocaill RM, Cleary M. Immediate Weight-Bearing Compared with Non-Weight-Bearing After Operative Ankle Fracture Fixation: Results of the INWN Pragmatic, Randomized, Multicenter Trial. J Bone Joint Surg Am. 2025 May 23;107(13):1423-1438. doi: 10.2106/JBJS.24.00965. PMID: 40408465. https://bit.ly/4pMR5BR • Lawson MM, Lancaster K, Lipps C, Slobogean G, Brady JM, O'Hara N, Working ZM. Home Call and Sleep in Orthopaedic Surgeons: A Prospective, Longitudinal Study of the Effect of Home Call on Sleep in Orthopaedic Attending Surgeons and Residents. J Bone Joint Surg Am. 2025 Oct 15;107(20):2235-2242. doi: 10.2106/JBJS.24.01411. Epub 2025 Aug 20. PMID: 40834105. https://bit.ly/4anUpOS • Harris AB, Vigdorchik JM, Khanuja HS, Hegde V. Modern Alignment Strategies in Total Knee Arthroplasty and How to Best Achieve Them. J Bone Joint Surg Am. 2025 Nov 5;107(21):2457-2468. doi: 10.2106/JBJS.25.00480. Epub 2025 Sep 12. PMID: 40938970. https://bit.ly/49gzlbY • Hannon CP, Salih R, Barrack RL, Nunley RM. Cementless Versus Cemented Total Knee Arthroplasty: Concise Midterm Results of a Prospective Randomized Controlled Trial. J Bone Joint Surg Am. 2023 Sep 20;105(18):1430-1434. doi: 10.2106/JBJS.23.00161. Epub 2023 Jun 22. PMID: 37347823. https://bit.ly/44UsJxJ Keywords: Orthopaedics, orthopedics, JBJS, OE, change in practice, moving the needle, creativity, impact, sleep, age, stage of career, cognitive decline, mistakes, robotics, alignment, function, revision, survivorship, AI, artificial intelligence, LLM, education, creativity