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OrthoJOE

36. AAOS Clinical Practice Guidelines on OA of the Knee (3rd Edition)

In this episode, Marc and Mo discuss the third edition of the AAOS Clinical Practice Guidelines on Osteoarthritis of the Knee, with a particular focus on the quality of evidence related to injectable therapies and the concept of “living guidelines.” OrthoJOE Mailbag: feedback, comments, and suggestions from our audience can be sent to orthojoe@jbjs.org Links: • AAOS Clinical Practice Guidelines on Osteoarthritis of the Knee (originally released in 2013, update in Aug. 2021 (https://www.aaos.org/quality/quality-programs/lower-extremity-programs/osteoarthritis-of-the-knee/) • Vannabouathong C, Bhandari M, Bedi A, Khanna V, Yung P, Shetty V, Khan M. Nonoperative Treatments for Knee Osteoarthritis: An Evaluation of Treatment Characteristics and the Intra-Articular Placebo Effect: A Systematic Review. JBJS Rev. 2018 Jul;6(7):e5. doi: 10.2106/JBJS.RVW.17.00167. https://jbjs.org/reader.php?rsuite_id=1734831&native=1&source=JBJS_Reviews/6/7/e5/fulltext&topics=kn#info • Bauer TW. Stem Cell Therapy for Knee Pain—What Exactly Are We Injecting, and Why? Editorial. J Bone Joint Surg. 2016 Sep; 98(15): 1509. doi: 10.2106/JBJS.16.00872. https://jbjs.org/reader.php?rsuite_id=1261189&native=1&source=The_Journal_of_Bone_and_Joint_Surgery/98/18/1509/fulltext&topics=bs#info Keywords: Orthopaedics, JBJS, OrthoEvidence, AAOS, CPG, OA, viscosupplementation, injectables, platelet-rich plasma, PRP, hyaluronic acid, HA, corticosteroids, changes in practice, grades of evidence, NSAIDs, acetaminophen, exercise, patient education, braces, MCID, minimum clinically important difference, 95% CI, manufacturing processes, low-molecular-weight HA, high-molecular-weight HA, living meta-analysis, living guideline, signal-to-noise ratio

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